Chairmen : Michel DE WAARD & Lhousseine TOUQUI

• 9h10 - 9h40 : Lhousseine TOUQUI

  Mucoviscidose et Bronchopathies Chroniques, Institut Pasteur, Paris, France

  Immunomodulatory roles of bacterial toxins: impacts on the innate pulmonary

  defense of the host 

• 9h40 - 10h10 : Christine BEETON

  Baylor College of Medicine, Houston, USA

• 10h10 - 10h30 : Nassim MAHTAL 
  Service d’Ingénierie Moléculaire des Protéines, CEA de Saclay, Gif-sur-Yvette, France 
  High-Throughput Screening of Rac1 enhancers as stimulators of innate and acquired immunity
• 10h30 – 10h50: Fatima CHGOURY 
  Laboratoire des Venins et Toxines, Institut Pasteur du Maroc, Casablanca, Maroc
  Paraspecific effect of Androctonus australis hector NbF12-10 nanobody against Moroccan scorpion venom
• 10h50 – 10h55: Conrad WEICHBRODT 
  Nanion Technologies GmbH, München, Germany
  Next level toxicity screening: from single channel to overall cell behavior

• 10h55 – 11h25: Coffee break & Posters 
  
  
• 11h25 – 11h55: Philipp HENNEKE 
  Center for Chronic Immunodeficiency, Freiburg, Germany
  Macrophage subset development and environmental imprinting determine immunity in staphylococcal soft tissue infection
• 11h55 – 12h25: Philippe BULET 
  Plateforme BioPark d'Archamps, Archamps Technopole, Saint Julien en Genevois, France
  Venom toxins and antimicrobial peptides: evidence that venom toxins are closely related to defensins of innate immunity
• 12h25 – 12h45: Michel DE WAARD 
  Institut du Thorax, Nantes, France
  Efficient neutralization of deadly toxins in vivo by DNA oligonucleotides

• 12h45 – 14h30: Lunch & Posters

Chairmen: Denis SERVENT & Eric LINGUEGLIA

• 14h30 – 15h00: Laurence BOURGEAIS RAMBUR 
  Centre de Psychiatrie & Neurosciences, Paris, France
  Functional architecture of pain pathways
• 15h00 – 15h30: Estelle MARION 
  ATOMyca, Angers, France
  Mycolactone: the amazing analgesic mycobacterial toxin
• 15h30 – 15h50: Tânia C. GONÇALVES 
  Sanofi R&D, Vitry-sur-Seine, France
  D peptide, a promising toxin as potential antinociceptive agent targeting the Nav1.7 subtype of voltage-gated sodium channels
• 15h50 – 16h20: Ren LAI 
  Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
  Centipede venom toxins acting on ion channels
• 16h20 – 16h50: Eric LINGUEGLIA 
  Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France
  Acid-Sensing Ion Channels in the pain pathway or how animal toxins can help to understand pain
• 16h50 – 17h20: Mikhail KALINICHEV 
  Ipsen Innovation, Les Ulis, France
  Exploiting the biology of botulinum neurotoxins for pain

• 17h30 – 19h00: General Assembly of the SFET (SFET members)

Chairmen: Grazyna FAURE & Félix VIANA

• 9h00 – 9h30: Jean-Marc CAVAILLON 
  Unité Cytokines et Inflammation, Institut Pasteur, Paris, France
  Exotoxins and endotoxins: inducers of inflammatory cytokines
• 9h30 – 10h00: Michel R. POPOFF 
  Unité des Bactéries anaérobies et Toxines, Institut Pasteur, Paris, France
  Toxins of Clostridium sordellii and Clostridium difficile: the proinflammatory versus cytoprotective response
• 10h00 – 10h20: Joseph KHOURY 
  Biologie neurovasculaire et mitochondriale intégrée, Université d’Angers, France
  The aqueous buds extract of Eucalyptus neutralizes the main enzymatic activities of Montivipera bornmuelleri venom

• 10h20 – 10h50: Coffee break & Posters

• 10h50 – 11h20: Michael HENEKA 
  Clinical Neuroscience Unit, Department of Neurology, University of Bonn, Germany
  Does neuroinflammation represent a promising therapeutic target in Alzheimer's disease?
• 11h20 – 11h50: Félix VIANA 
  Instituto de Neurociencias de Alicante, Universidad Miguel Hernández y CSIC, Alicante, Spain
  TRPA1 channels: molecular sentinels of cellular stress and tissue damage
• 11h50 – 12h10: Jean-David MOREL 
  Unité d’Immunobiologie de l’Infection, Institut Pasteur, Paris, France
  Host immunomodulation by mycolactone, the Mycobacterium ulcerans toxin

• 12h10 – 15h00: Lunch & Posters

Chairmen: Sébastien DUTERTRE & Jordi MOLGÓ

• 15h00 – 15h20: Alexander BELYY 
  Unité de Biochimie des Interactions macromoléculaires, Institut Pasteur, Paris, France
  Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin
• 15h20 – 15h40: Naoual OUKKACHE 
  Laboratoire des Venins et Toxines, Institut Pasteur du Maroc, Casablanca, Maroc
  Characterization of Am IT, an anti-insect β-toxin isolated from the venom of scorpion Androctonus mauretanicus
• 15h40 – 16h00: Laura DROCTOVE 
  Service d’Ingénierie Moléculaire des Protéines, CEA de Saclay, Gif-sur-Yvette, France
  Crystal structure and functional domains of the Mambaquaretin-1, a vasopressin type 2 receptor peptide inhibitor for kidney cysts treatment
• 16h00 – 16h20: Alexandre CHENAL 
  Département de Biologie structurale et Chimie, Institut Pasteur, Paris, France
  Calcium tightly regulates disorder-to-order transitions involved in the secretion, folding and functions of the CyaA toxin of Bordetella pertussis, the causative agent of whooping cough
• 16h20 – 16h40: Justyna CIOLEK 
  Service d’Ingénierie Moléculaire des Protéines, CEA de Saclay, Gif-sur-Yvette, France
  Muscarinic toxin 9: a novel peptide from Dendroaspis polylepis venom that selectively targets muscarinic type 2 receptor
• 16h40 – 17h00: Romulo ARAOZ 
  Service d’Ingénierie Moléculaire des Protéines, CEA de Saclay, Gif-sur-Yvette, France
  Vulcanodinium rugosum (French-isolate) producer of pinnatoxin-G, also synthesizes portimine, a potent inducer of apoptosis, that also acts as an antagonist of nicotinic acetylcholine receptors

• 17h00 – 17h10: Closure. Evelyne BENOIT (SFET President)