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RT23 (2016) : Toxins: Immunity, Inflammation and Pain Version imprimable Suggérer par mail

23rd Meeting of the French Society of Toxinology (SFET)

"Toxins: Immunity, Inflammation and Pain"

5 et 6 Décembre 2016 - Institut Pasteur (Auditorium François Jacob)
Paris - France




9h10 - 12h45 : Session 1 | Toxins and Immunity

Chairmen : Michel DE WAARD & Lhousseine TOUQUI


  • 9h10 - 9h40 : Lhousseine TOUQUI

  Mucoviscidose et Bronchopathies Chroniques, Institut Pasteur, Paris, France

  Immunomodulatory roles of bacterial toxins: impacts on the innate pulmonary

  defense of the host 

  • 9h40 - 10h10 : Christine BEETON

  Baylor College of Medicine, Houston, USA

  Targeting potassium channels in rheumatoid arthritis 
  • 10h10 - 10h30 : Nassim MAHTAL
    Service d’Ingénierie Moléculaire des Protéines, CEA de Saclay, Gif-sur-Yvette, France
    High-Throughput Screening of Rac1 enhancers as stimulators of innate and acquired immunity
  • 10h30 – 10h50: Fatima CHGOURY
    Laboratoire des Venins et Toxines, Institut Pasteur du Maroc, Casablanca, Maroc
    Paraspecific effect of Androctonus australis hector NbF12-10 nanobody against Moroccan scorpion venom
  • 10h50 – 10h55: Conrad WEICHBRODT
    Nanion Technologies GmbH, München, Germany
    Next level toxicity screening: from single channel to overall cell behavior

  • 10h55 – 11h25: Coffee break & Posters

  • 11h25 – 11h55: Philipp HENNEKE
    Center for Chronic Immunodeficiency, Freiburg, Germany
    Macrophage subset development and environmental imprinting determine immunity in staphylococcal soft tissue infection
  • 11h55 – 12h25: Philippe BULET
    Plateforme BioPark d'Archamps, Archamps Technopole, Saint Julien en Genevois, France
    Venom toxins and antimicrobial peptides: evidence that venom toxins are closely related to defensins of innate immunity
  • 12h25 – 12h45: Michel DE WAARD
    Institut du Thorax, Nantes, France
    Efficient neutralization of deadly toxins in vivo by DNA oligonucleotides

  • 12h45 – 14h30: Lunch & Posters


14h30 - 17H20: Session 2 | Toxins and Pain

Chairmen: Denis SERVENT & Eric LINGUEGLIA


  • 14h30 – 15h00: Laurence BOURGEAIS RAMBUR
    Centre de Psychiatrie & Neurosciences, Paris, France
    Functional architecture of pain pathways
  • 15h00 – 15h30: Estelle MARION
    ATOMyca, Angers, France
    Mycolactone: the amazing analgesic mycobacterial toxin
  • 15h30 – 15h50: Tânia C. GONÇALVES
    Sanofi R&D, Vitry-sur-Seine, France
    D peptide, a promising toxin as potential antinociceptive agent targeting the Nav1.7 subtype of voltage-gated sodium channels
  • 15h50 – 16h20: Ren LAI
    Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
    Centipede venom toxins acting on ion channels
  • 16h20 – 16h50: Eric LINGUEGLIA
    Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France
    Acid-Sensing Ion Channels in the pain pathway or how animal toxins can help to understand pain
  • 16h50 – 17h20: Mikhail KALINICHEV
    Ipsen Innovation, Les Ulis, France
    Exploiting the biology of botulinum neurotoxins for pain

  • 17h30 – 19h00: General Assembly of the SFET (SFET members)

Session 3 | Toxins and Inflammation

Chairmen: Grazyna FAURE & Félix VIANA


  • 9h00 – 9h30: Jean-Marc CAVAILLON
    Unité Cytokines et Inflammation, Institut Pasteur, Paris, France
    Exotoxins and endotoxins: inducers of inflammatory cytokines
  • 9h30 – 10h00: Michel R. POPOFF
    Unité des Bactéries anaérobies et Toxines, Institut Pasteur, Paris, France
    Toxins of Clostridium sordellii and Clostridium difficile: the proinflammatory versus cytoprotective response
  • 10h00 – 10h20: Joseph KHOURY
    Biologie neurovasculaire et mitochondriale intégrée, Université d’Angers, France
    The aqueous buds extract of Eucalyptus neutralizes the main enzymatic activities of Montivipera bornmuelleri venom

  • 10h20 – 10h50: Coffee break & Posters

  • 10h50 – 11h20: Michael HENEKA
    Clinical Neuroscience Unit, Department of Neurology, University of Bonn, Germany
    Does neuroinflammation represent a promising therapeutic target in Alzheimer's disease?
  • 11h20 – 11h50: Félix VIANA
    Instituto de Neurociencias de Alicante, Universidad Miguel Hernández y CSIC, Alicante, Spain
    TRPA1 channels: molecular sentinels of cellular stress and tissue damage
  • 11h50 – 12h10: Jean-David MOREL
    Unité d’Immunobiologie de l’Infection, Institut Pasteur, Paris, France
    Host immunomodulation by mycolactone, the Mycobacterium ulcerans toxin

  • 12h10 – 15h00: Lunch & Posters



Session 4| Miscellaneous

Chairmen: Sébastien DUTERTRE & Jordi MOLGÓ


  • 15h00 – 15h20: Alexander BELYY
    Unité de Biochimie des Interactions macromoléculaires, Institut Pasteur, Paris, France
    Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin
  • 15h20 – 15h40: Naoual OUKKACHE
    Laboratoire des Venins et Toxines, Institut Pasteur du Maroc, Casablanca, Maroc
    Characterization of Am IT, an anti-insect β-toxin isolated from the venom of scorpion Androctonus mauretanicus
  • 15h40 – 16h00: Laura DROCTOVE
    Service d’Ingénierie Moléculaire des Protéines, CEA de Saclay, Gif-sur-Yvette, France
    Crystal structure and functional domains of the Mambaquaretin-1, a vasopressin type 2 receptor peptide inhibitor for kidney cysts treatment
  • 16h00 – 16h20: Alexandre CHENAL
    Département de Biologie structurale et Chimie, Institut Pasteur, Paris, France
    Calcium tightly regulates disorder-to-order transitions involved in the secretion, folding and functions of the CyaA toxin of Bordetella pertussis, the causative agent of whooping cough
  • 16h20 – 16h40: Justyna CIOLEK
    Service d’Ingénierie Moléculaire des Protéines, CEA de Saclay, Gif-sur-Yvette, France
    Muscarinic toxin 9: a novel peptide from Dendroaspis polylepis venom that selectively targets muscarinic type 2 receptor
  • 16h40 – 17h00: Romulo ARAOZ
    Service d’Ingénierie Moléculaire des Protéines, CEA de Saclay, Gif-sur-Yvette, France
    Vulcanodinium rugosum (French-isolate) producer of pinnatoxin-G, also synthesizes portimine, a potent inducer of apoptosis, that also acts as an antagonist of nicotinic acetylcholine receptors

  • 17h00 – 17h10: Closure. Evelyne BENOIT (SFET President)  

Dernière mise à jour : ( 30-06-2017 )

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