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RT19 (2011) : Toxins and Ion Transfers Version imprimable Suggérer par mail
  • Welcome. Denis SERVENT (SFET President)

  • Session Toxins and Ion Channels
    Chairman : Marie-France Martin-Eauclaire, Christian Legros Session

  • Frank Bosmans
    (Porter Neuroscience Research Center, National Institutes of Health, Bethesda and Johns Hopkins Medical School – Physiology Department, Baltimore, USA)
    Function and pharmacology of sodium channel voltage sensors
  • Marie-France Martin-Eauclaire
    (ToxCiM, Dept. Signalisation Neuronale, Centre de Recherches en Neurobiologie-Neurophysiologie de Marseille, France)
    Overview of the small Kv channels blockers from Androctonus venoms
  • Sylvie Diochot
    (Institut de Pharmacologie Moléculaire et Cellulaire, Université de Nice-Sophia-Antipolis, France)
    Analgesic properties of APETx2, a sea anemone peptide inhibiting ASIC3, in inflammatory and post-operative pain models
  • Jordi Molgo
    (Institut de Neurobiologie Alfred Fessard, CNRS, Gif sur Yvette, France) Pinnatoxins: an emergent family of marine phycotoxins targeting nicotinic acetylcholine receptors with high affinity

  • Stefan Heinemann
    (Center for Molecular Biomedicine, University of Jena, Germany)
    Modulation of voltage-gated sodium channels with peptide toxins
  • Jan Siemens
    (Max-Delbrück Center for Molecular Medicine, Berlin, Germany)
    A bivalent tarantula toxin produces inflammatory pain by targeting the outer pore domain of the capsaicin receptor TRPV1
  • Bruno Lapied
    (Laboratoire Récepteurs et Canaux Ioniques Membranaires, Université d’Angers, France)
    Neurotoxic action of the repellent DEET occurs through positive and negative allosteric modulation of muscarinic acetylcholine receptors

  • Poster session

  •  Session Pore-Forming Toxins I
    Chairmen : Daniel Ladant, Cesare Montecuccco

  • Vittorio Ricci
    (Department of Physiology, University of Pavia, Italy)
    VacA from Helicobacter pylori: journey and action mechanism in epithelial cells
  • Joachim Rassow
    (Institut für Physiologische Chemie, Bochum, Germany)
    Targeting of Helicobacter pylori VacA to mitochondria
  • Michel Popoff
    (Unité des Bactéries anaérobies et Toxines, Institut Pasteur, Paris, France)
    Clostridium perfringens epsilon toxin; a fascinating pore-forming toxin
  • Ajit K. Basak
    (Department of Biological Sciences, Birkbeck College, London, UK)
    Structural Studies Reveal Novel Relationships betwee Clostridium perfringens Pore-forming Toxins
  • Roland Benz
    (Rudolf-Virchow-Center, University of Würzburg, Germany)
    Influences of His-tag in the Uptake of Different Effectors Promoted by Anthrax Protective Antigen and C2II: A Possible Selective Translocation System Revealed
  •  Gilles Prevost
    (Physiopathologie et Médecine Translationnelle, Université Louis Pasteur, Strasbourg, France)
    General and particular inhibitions of the staphylococcal leucotoxin functions

  • General Assembly of the SFET (J. Monod Amphitheatre) 



  • Session Pore-Forming Toxins II
    Chairmen : Michel Popoff, Vittorio Ricci

  • Rod Tweten
    (University of Oklahoma Sciences Center, Oklahoma City, USA)
    The Cholesterol-Dependent Cytolysins: Molecular Mechanism to Vaccine Development
  • Alexandre Chenal
    (Unité de Biochimie des Interactions Macromoléculaires, Institut Pasteur, Paris, France)
    Diphtheria toxin: coupling of pore-forming and translocation activities
  • Cesare Montecucco
    (Dipartimento di Scienze Biomediche, Universitá di Padova, Italy)
    Tetanus and botulinum neurotoxins need to have two feet on the membrane to enter neurons
  • Philippe Sansonetti
    (Unité de pathogénie Microbienne Moléculaire, Institut Pasteur, Paris, France)
    Antimicrobial peptides at mucosal surface: complex ensuring of a bacterial exclusion zone
  • Gregor Anderluh
    (Department of Biology, University of Ljubljana, Slovenia)
    How pore forming toxins recognise sphingomyelin

  • Posters session

  • Session Toxins as Tools and Therapeutics
    Chairmen : Richard Lewis, Pierre Escoubas

  • Ines Ibanez-Tallon
    (Department of Neuroscience, Max Delbrück Center for Molecular Medicine, Berlin, Germany)
    From ion channels to behavior: in vivo dissection of circuits controlling pain and addiction
  • Michel Partiseti
    (Sanofi-Aventis, Vitry sur Seine, France)
    Moving away from small molecules in ion channel discovery: opportunities and challenges
  • Holger Barth
    (University of Ulm Medical Center, Ulm, Germany)
    Tailored ß-cyclodextrin blocks membrane translocation of binary exotoxins from Clostridium botulinum and Clostridium perfringens and protects mammalian cells from intoxication

  • Poster session

  • Richard Lewis
    (Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia)
    Ion channel toxins for drug discovery and development
  • Nicolas Gilles
    (Laboratoire de Toxinologie Moléculaire et Biotechnologie, CEA/iBiTecS, Saclay, France)
    G protein-coupled receptors, an unexploited family of animal toxin targets: Exploration of green mamba venom for novel ligands of adrenoceptors
  • Pierre Escoubas
    (VenomeTech, Nice, France)
    Development of a parallel refolding platform for disulfide-linked peptides
  • Marion Tarbe
    (UMR-6264, Laboratoire Chimie Provence, Marseille, France)
    KITOXAN®, a Venom Fraction Library to Accelerate the Identification of Anti-angiogenic Peptides
  • Naziha Marrakchi
    (Laboratory of Venoms Toxins, Pasteur Institute of Tunis, Tunisia)
    Anti-tumoral snake venoms peptides

  • Session Miscellaneous
    Chairwoman : Grazyna Faure

  • Marie-Laure Pinel
    (Faculté de Pharmacie, Université de Rennes, France)
    Dual function for an overlapping RNA pair expressed by S. aureus: One encodes a membrane polypeptide and the other is a down regulator
  • Frédéric Ducancel
    (Laboratoire d’Ingénierie des Anticorps pour la Santé, CEA/iBiTecS, Saclay, France)
    Interaction of engineered sarafotoxins with endothelin receptors
  • Emmanuel Jover
    (INCI – UPR-CNRS 3212 , Neurotransmission et sécrétion neuroendocrine, Strasbourg, France)
    Neurotoxicity Staphylococcus aureus Leucotoxins: interaction with the Store Operated Calcium Entry Complex in central and sensory neurons
  • Guillaume Blanchet
    (Laboratoire de Toxinologie Moléculaire et Biotechnologie, CEA/iBiTecS, Saclay, France)
    Aminergic toxins : When Green mamba produces GPCR tools

  • Closure. Denis SERVENT (SFET President)


Dernière mise à jour : ( 11-05-2012 )

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