"Toxins : From Threats to Benefits"

10 - 11 December 2012, Pasteur Institute, Paris - France

• Welcome. Denis SERVENT (SFET President)

• Marie-France Martin-Eauclaire
  Faculté de Médecine de Marseille, France
  History of the SFET

Session 1 - Threats: Exposure and Risks
Chairmen : Dietrich Mebs, Jorge Diogene

• Jorge Diogene
  IRTA, Ctra. Poble Nou, 43540 Sant Carles de la Ràpita, Spain
  Emerging Marine Toxins 
  

• Magalie Labadie
  Toxicologie Clinique. Centre antipoison et de toxicovigilance de Bordeaux, France
  Physalia envenimation

• Mélanie Roué
  IRD, Papeete, France
  Giant Clams: New vectors of ciguatera?

• Rómulo Aráoz
  Institut Fédératif de Neurobiologie Alfred Fessard, Gif-sur-Yvette, France
  Coupling a Torpedo microplate-receptor binding assay with mass spectrometry to detect freshwater and marine toxins acting on nicotinic acetylcholine receptor

• Max Goyffon
  MNHN, Paris, France.
  Snakebites by "harmless" snakes: What is a venomous snake? 

• Andy Pickett
  Toxin Science Limited, Wrexham, UK.
  Risks associated with botulinum toxin in clinical use 

• Didier Hilaire
  DGA MNRBC, Vert le Petit, France.
  Forensic identification of toxins classified as a threat agent for military or bioterrorist use

• Poster session - Vote for SFET-CA election

Session 2 - Genesis and Evolution
Chairmen : Juan Calvete, Daniel Ladant

• Michel Simonet
  Institut de Biologie de Lille, France.
  Bacterial toxins and mobile genetic elements 

• Michel Popoff
  Bactéries anaérobies et Toxines, Institut Pasteur, Paris.
  Evolution of Clostridial Toxins
  
• Juan Calvete
  Instituto de Biomedicina de Valencia, Valencia, Spain.
  Towards an integrated omics approach to understand venom evolution

• Ricardo C. Rodríguez de la Vega
  Laboratoire Ecologie, Systématique et Evolution, Université Paris-Sud, Orsay, France
  Convergence and divergence in animal venoms
  

• Guillaume Blanchet
  CEA, iBiTec-S, Service d’Ingénierie Moléculaire des Protéines, Gif-sur-Yvette, France
  An evolutionary approach of mamba venoms: ”le hasard et la nécessité”
  

• Pasteur Museum Visit - General Assembly of the SFET (SFET members)
• Gala Dinner  

Session 3 - Molecular and Cellular Targets

Chairmen : Michel Popoff, Jordi Molgó

• Holger Barth
  Institute of Pharmacology and Toxicology, University of Ulm Medical Center, Ulm, Germany
  Clostridium botulinum C3 protein: A novel transporter for selective delivery of proteins into the cytosol of monocytes/macrophages
  

• Andreas Rummel
  Institut für Toxikologie, Medizinische Hochschule Hannover, Hannover, Germany
  The biological activity of botulinum neurotoxins

• Cesare Montecucco
  Università degli Studi di Padova, Padova, Italy
  Membrane translocation of tetanus and botulinum neurotoxins

• Mauricio Montal
  University of California San Diego
  Blocking botulism: A journey into modules and modulators
  

• Laetitia Wioland
  Institut des Neurosciences Cellulaires et Intégratives, Strasbourg, France
  Clostridium perfringens Epsilon Toxin acts on granule cells and on oligodendrocytes leading to demyelination
  
• Alexandre Chenal
  Pasteur Institute, Paris, France
  Calcium-induced folding of intrinsically disordered RTX proteins: Implications for RTX toxin physiology

• Aurelia Tubaro
  Agriculture and Environmental Sciences Department, University of Udine, Udine, Italy
  Toxicological effects of palytoxin and yessotoxin

• Angélique Vétillard
  Equipe Venin et activité biologique, Université de Toulouse, France
  Transcriptome analysis of expressed sequence tags (ESTs) from the venom glands of the ant species Tetramorium bicarinatum (Hymenoptera: Formicidae)

• Poster session

Session 4 - Benefits: Toxinotherapeutics
Chairmen : Mike Pennington, Sylvie Diochot

• Daniel Gillet
  CEA, iBiTec-S, Service d’Ingénierie Moléculaire des Protéines, Gif sur Yvette, France
  Inhibitor of HB-EGF derived form diphtheria toxin, for the treatment of HB-EGF-related diseases
  
• Mike Pennington
  Peptides International, 11621 Electron Drive, Louisville, KY 40299, USA
  Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases

• Adrijana Leonardi
  Department of Molecular and Biomedical Sciences, Jožef Stefan Institute, Ljubljana, Slovenia
  Discovering innovative drugs and diagnostic tools to control haemostasis by venomics of the Vipera a. ammodytes snake
  
• Sylvie Diochot
  IPMC, Université Nice-Sophia Antipolis, Valbonne, France
  Black mamba venom peptides target acid-sensing ion channels to abolish pain
  

• Grazyna Faure
  Pasteur Institute, Paris, France
  Correcting effect of PLA2 subunit of crotoxin on mutated CFTR: original perspective to investigate the pharmacotherapy of Cystic Fibrosis 

• Marion Verdoni
  Institut de Chimie Radicalaire, Faculté des Sciences et Techniques, Université Aix-Marseille, France
  For the first time, new inhibitors peptides of melanogenesis isolated from venoms
  

• Closure. Denis SERVENT (SFET President)